Breast cancer remains a leading cause of cancer-related mortality worldwide. This has led to the continuous search for novel and effective therapeutic agents. Triazoles, a class of five-membered heterocyclic compounds containing three nitrogen atoms, have demonstrated significant anticancer potential due to their ability to inhibit key biological pathways involved in tumor progression. This study investigates the cytotoxic effects of various triazole derivatives on breast cancer cells, assessing their efficacy through in vitro assays. Previous studies suggest that specific triazole derivatives exhibit some anticancer activity, highlighting their potential as therapeutic agents for breast cancer treatment. Further studies are warranted to elucidate their molecular targets and optimize their pharmacological properties.