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GS4 Student Scholars Symposium
Venue: Savannah Ballroom (211A) clear filter
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Tuesday, April 22
 

10:00am EDT

A Cell-Permeant Degrader Based on a PRL3 Nanobody, NB91
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Nanobodies (Nb) are small proteins derived from the variable region of heavy chain only antibodies of camelids. Nbs can be used as therapeutics and in diagnostics as they can be engineered for high target affinity and their size means they can penetrate tissues more effectively. They can also be produced in E. coli and are therefore cheaper and easier to produce than monoclonal antibodies. Recently, a nanobody degrader was developed that utilizes a miniprotein to deliver a nanobody attached to an E3 adaptor to recruit ubiquitin ligase. The Nb recognizes a target and directs it for degradation. NB91 is a high-affinity PRL3 nanobody previously developed. We are using it to construct a cell permeable degrader that can be used against PRL3 as an alternative to small molecule inhibitors. PRL3 is an established target for various cancers and a PRL3 degrader can be developed for clinical applications.
Speakers
GB

Grace Bennett

gs09195@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
HC

Hailey Chen

hc09542@georgiasouthern.edu, College of Science and Mathematics
GB

Gracie Bliss

gb11209@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

A Generative Approach to Improving Spanish Articulation in Non-Native Speakers
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
The purpose of the study was to examine whether instruction on underlying component articulation skills using video models, discrimination training, and TAGteaching can improve the dialect of spoken Spanish in non-native Spanish speakers. Results showed that all three participants improved their articulation and even had growth in sounds non-targeted for intervention. 
Speakers
avatar for Laura Mican

Laura Mican

lm24625@georgiasouthern.edu, College of Behavioral and Social Science
AB

Andrew Bulla

abulla@georgiasouthern.edu, College of Behavioral and Social Science
LV

Lindsey Villeda

lv02627@georgiasouthern.edu, College of Science and Mathematics
JM

Jennifer Macias

jm57486@georgiasouthern.edu, College of Science and Mathematics
LP

Laura Pompa

lp12889@georgiasouthern.edu, College of Science and Mathematics
JG

Joselyn Gaspar

jg36105@georgiasouthern.edu, College of Science and Mathematics
EC

Encarnación Cruz Jiménez

encarnicruz@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

A Preliminary Investigation of Eye-Tracking Software to Inform an ABA Renewal Mitigation Procedure
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
ABA renewal is a treatment relapse phenomenon in which previously extinguished target behavior recurs upon returning to a familiar context. In renewal, a target response may receive reinforcement in an original context, referred to as Context A, but is extinguished in a separate context, referred to as Context B. Despite extinction, rates of target responding may be observed when the individual is returned to Context A. One method to mitigate renewal is to increase similarity between contexts by programming stimuli across both Contexts A and B. The current investigation had 31 college undergraduate students participate in a three-phase ABA renewal arrangement implementing differential reinforcement of alternative responses in a translational preparation. The results replicated previous research observing ABA renewal phenomena despite differential reinforcement and further observed that renewal may be less robust and more variable when stimuli are programmed using eye-tracking software.
Speakers
avatar for Kayla Randall

Kayla Randall

krandall@georgiasouthern.edu, College of Behavioral and Social Science
Dr. Randall is a Board Certified Behavior Analyst at the doctoral level and Assistant Professor at Georgia Southern University. She earned a Master’s of Education degree in Special Education from Vanderbilt University. She earned a doctoral degree in Applied Behavior Analysis from... Read More →
CL

Cameron Long

cl17012@georgiasouthern.edu, Jack Averitt College of Graduate Studies
SE

Seth England

se07210@georgiasouthern.edu, College of Graduate Studies
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

A Retrospective Analysis of Neuroinvasive Cases of West Nile Virus in New York State
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
West Nile Virus (WNV) is the leading cause of mosquito-borne vector diseases in the U.S., primarily transmitted by Culex mosquitoes and maintained in bird reservoirs. It often presents with central nervous system symptoms such as encephalitis, meningitis, seizures, and altered mental status, with no FDA-approved treatment beyond supportive care. This study examined the prevalence of neuroinvasive WNV (nWNV) in New York State from 1999 to 2023, analyzing its distribution across counties classified as Atlantic Ocean (AO)-bordered, Great Lakes (GL)-bordered, or landlocked (LL). Using a Generalized Linear Model (GLM) with a Poisson distribution, twelve counties, including Bronx, Nassau, and Queens, showed significant associations with nWNV cases (p < 0.01). AO counties had the highest susceptibility compared to GL (β = -2.74, p < 2×10⁻¹⁶) and LL counties (β = -4.11, p < 2×10⁻¹⁶). These findings emphasize the role of standing water in disease transmission and the need for increased public health awareness.
Speakers
SJ

Stanley Joseph

stjoseph@augusta.edu, Medical College of Georgia - Savannah Campus
CS

Christina Skariah

cjohnson1754@gmail.com, Medical College of Georgia - Savannah Campus
JS
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

A Systematic Replication Comparing the Efficiency and Effectiveness of Restricted- and Free-Operant Programming on Measures of Acquisition and Fluency
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Discrete-trial teaching (DTT), a restricted-operant teaching arrangement, and frequency-building instruction (FBI), a free-operant teaching arrangement, represent two instructional strategies derived from operant conditioning. Researchers and practicing behavior analysts have used both to establish and firm up novel stimulus-behavior relations. Despite the effectiveness of both procedures, few studies have compared the two techniques and assessed the effects on the emergence of fluent responding. The current study extends the research to typically developing college students to directly compare DTT and FBI. We taught participants the numerals 0-10 in unknown foreign languages (i.e., Mandarin, Arabic, and Hindi) using both procedures. Under both conditions, we held constant the number of practice trials and frequency of reinforcement. Results found quicker acquisition under restricted-operant conditions for all participants, though none of the participants met the desired frequency aim prior to the end of the study. We discuss the results of the study in the context of planning for learning across three stages of learning.
Speakers
AS

Allison Sullivan

as58857@georgiasouthern.edu, College of Behavioral and Social Science
JW

Jennifer Wertalik

jwertalik@georgiasouthern.edu, College of Behavioral and Social Science
AB

Andrew Bulla

abulla@georgiasouthern.edu, College of Behavioral and Social Science
MP

Michaela Porter

mp22130@georgiasouthern.edu, College of Behavioral and Social Science
SS

Sophia Schawrtz

College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

AI for Intelligent Commerce Evolution
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Accurately predicting consumer purchasing behavior is a cornerstone of effective inventory management and targeted marketing strategies. The rapid evolution of Artificial Neural Networks (ANNs), combined with unprecedented access to high-quality, real-time consumer data, has paved the way for more sophisticated and precise predictive models. Leveraging these advancements, this research focuses on developing a cutting-edge predictive model utilizing Long Short-Term Memory (LSTM) neural networks to assess the likelihood of consumer purchases with high accuracy.
Our approach involves analyzing intricate behavioral patterns by tracking a consumer's sequence of interactions leading up to a purchase—or abandonment—using real-world data from an online shopper purchasing intention dataset. By capturing the temporal dependencies within consumer actions, LSTM models enable us to decode subtle decision-making patterns and anticipate purchasing intent with greater precision.
Speakers
RS

Rene Soto Calzadilla

rs11659@georgiasouthern.edu, Allen E. Paulson College of Engineering and Computing
FH

Felix Hamza-Lup

fhamzalup@georgiasouthern.edu, College of Engineering and Computing
IE

Ionut Emil Iacob

ieiacob@georgiasouthern.edu, College of Behavioral and Social Science
MD
AL
HJ
AP

Akshar Patel

ap33036@georgiasouthern.edu
AM
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

An Examination of Academic Performance: Effects of School Level and Problematic Substance Use
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
This study investigates how the progression of a collegiate academic school level could affect academic performance and how the severity of the level of problematic substance use alters the college student’s academic outcome. Previous studies observed that the effects of problematic substance use included negative impacts on cognitive functioning and academic performance. Our findings suggest that academic performance generally improves as students advance through their collegiate years, with a noticeable improvement between the sophomore and junior years. This increase is likely due to developing more effective study habits and time management skills. On the other hand, academic performance was found to be lower among students reporting higher levels of problematic substance use. As substance use severity increased, academic performance, including GPA, tended to decline. These results highlight the need for early identification of substance use issues and intervention to support students’ academic success.
Speakers
avatar for Virginia Wickline

Virginia Wickline

vwickline@georgiasouthern.edu, College of Behavioral and Social Science
SB

Samantha Bennett

sb24868@georgiasouthern.edu, College of Behavioral and Social Science
AM

Asialynn McCall

am52209@georgiasouthern.edu, College of Behavioral and Social Science
SC

Shukura Chism

College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

An Examination of Racial Differences in Photo Editing
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
While research on social media use has been extensive, the effects of selfie photo editing remain under examined, particularly regarding racial differences. McGovern et al. (2022) highlighted the need for further research, as most studies have relied on predominantly Caucasian samples. The current study examines racial differences in photo investment and editing behaviors among American college students. This study uses an online Qualtrics survey in which the participants take the The Revised Photo Investment Scale, Revised Self-Photo Manipulation Scale, Body Surveillance subscale of the Objectified Body Conscious Scale, and the Revised Physical Appearance Comparison Scale. Preliminary findings indicate that Caucasian females engage in more self-photo manipulation than African American females, particularly in facial and body modifications. However, no significant racial differences were found in photo investment. Data collection is ongoing, now including male participants, and further analysis will explore factors that may influence racial differences in photo editing behaviors.
Speakers
SF

Samira Farmer

cm40338@georgiasouthern.edu, College of Behavioral and Social Science
WW

Wendy Wolfe

wlwolfe@georgiasouthern.edu, College of Behavioral and Social Science
CS

Caden Stalnaker

College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Analyzing the impact of meditation on ADHD treatment through EEE signal
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental condition characterized by persistent inattention, hyperactivity, and impulsivity. Traditional treatments, such as medication and behavioral therapy, have shown varying degrees of success, but the potential benefits of alternative therapies like meditation are gaining attention. This study explores the impact of meditation on ADHD treatment through the analysis of EEG (electroencephalogram) signals. By examining changes in brainwave patterns during and after meditation sessions, we aim to understand how meditation may influence cognitive functions commonly affected by ADHD. Preliminary findings suggest that meditation may enhance attention, reduce hyperactivity, and increase mental focus, as evidenced by altered EEG activity, particularly in the theta and alpha frequency bands. These results imply that meditation could serve as a complementary tool in managing ADHD symptoms, offering a non-pharmacological option for treatment. Further research is necessary to validate these findings and optimize meditation-based interventions.
Speakers
WM

William Mahler

wm07256@georgiasouthern.edu, Allen E. Paulson College of Engineering and Computing
MV

Meenalosini Vimal Cruz

mvimalcruz@georgiasouther.edu, College of Engineering and Computing
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Analyzing the impact of meditation on Autism treatment through EEE signal
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
This presentation looks at how meditation affects autism treatment. We did that by reviewing studies that analyze EEG (Electroencephalography) signal changes in individuals with ASD (Autism Spectrum Disorder). Through a literature review, we summarize key findings on how meditation influences brain activity in ASD. The research suggests that meditation can positively change EEG patterns, which may be linked to improvements in focus, emotional balance, and overall well-being. This review helps to organize current knowledge and highlights the need for more research in this area. By presenting these findings, we aim to give a clearer picture of meditation’s role in ASD treatment.
Speakers
AS

Adrian Schoech

as51735@georgiasouthern.edu, Allen E. Paulson College of Engineering and Computing
MV

Meenalosini Vimal Cruz

mvimalcruz@georgiasouther.edu, College of Engineering and Computing
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Assessing the Effect of Education Level on Natural Language Processing Model Responses to Cardiovascular Disease Queries
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Cardiovascular disease (CVD) is the leading cause of death worldwide, and AI-powered natural language processing (NLP) models, such as ChatGPT and MediSearch, have the potential to improve patient education by providing accessible health information. This study evaluated the readability and similarity of CVD-related responses from ChatGPT Free (GPT-4o mini), ChatGPT Premium (GPT-4o), and MediSearch across three education levels: Lower Secondary, Higher Secondary, and College Graduate. FAQs on CVD were reformatted into user-friendly prompts and entered into each model. Readability was assessed using the Flesch-Kincaid Ease Score and Grade Level, while response similarity was analyzed using BERT embeddings with Cosine Similarity. Results showed that readability significantly decreased as education level increased (p<0.001), with ChatGPT Free providing the most accessible responses and MediSearch delivering more complex outputs. ChatGPT models demonstrated greater similarity to each other than to MediSearch. These findings emphasize the need for improved AI-driven medical communication tools.
Speakers
SJ

Stanley Joseph

stjoseph@augusta.edu, Medical College of Georgia - Savannah Campus
RH

Ryan Harris

ryharris@augusta.edu, Medical College of Georgia - Savannah Campus
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Beyond Words: Exploring Sarcasm Detection Using Eye-Tracking Technology.
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Traditional nonverbal cues like pitch and pupil dilation are increasingly unreliable, especially for nuanced communication like sarcasm. This study investigates gestural cues in sarcasm perception building on prior research that identifies the mouth and eyes as crucial. Sarcasm, prevalent yet potentially difficult to detect may benefit from nonverbal cues. We hypothesized that participants would better discern speaker intent with both audio and visual, and that eyes and mouth would be primary cues in video-only conditions.
Undergraduate participants viewed videos from the RISC database, with or without audio, and identified speaker intent (literal, humor, sarcasm, white lie). They then reported which gestural cues aided their perception: eyes, mouth, eyebrows, etc. Eye-tracking technology was used to validate self-reported cues. We anticipate eye tracking data will support self-reported findings.
Speakers
JE

Jonathan E. Roberts

jeroberts@georgiasouthern.edu, College of Behavioral and Social Science
LB

Lexis Botello

lb22973@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Breaking Boundaries: Harnessing Ultrasound Elastography for Enhanced Breast Lesion Detection and Cancer Diagnosis
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
This review examines ultrasound elastography’s role in improving breast lesion detection and cancer diagnosis. Breast cancer is a major health concern, making early detection essential. Traditional imaging methods, like mammography and conventional ultrasound, have limitations, often leading to unnecessary biopsies. Ultrasound elastography, a non-invasive technique assessing tissue stiffness, aids in distinguishing malignant from benign lesions. By measuring tissue response to mechanical stress, elastography enhances diagnostic accuracy and reduces unnecessary procedures.

This review explores current research on elastography’s benefits and limitations. Studies suggest combining it with conventional ultrasound improves lesion characterization and diagnostic confidence. Future research should refine techniques, integrate machine learning, and conduct large-scale trials to validate effectiveness. Advancing elastography in breast cancer imaging could significantly enhance early detection and patient outcomes. Continued research and technological development are needed to maximize its potential.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
BS

Britannia Samuels

bs22594@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Building Connections Through Communication and Community: Volunteering at a Camp for Adults with Williams Syndrome
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Camp Blue Skies was created to provide an enriching camp experience for adults with developmental disabilities, such as individuals with Williams Syndrome. Campers can socialize, learn, and have fun through various recreational and skill-building activities. Williams Syndrome is a rare genetic disorder that affects development, causing strong social and verbal skills but challenges with cognitive function, social boundaries, and spatial reasoning. Volunteers play an essential role in the success of camp operations and enhancing the campers’ experience. As students studying Communication Sciences and Disorders, we will reflect on our service-learning experience supporting campers with Williams Syndrome to highlight observed communication challenges and personal insights. Ultimately, we will discuss effective communication strategies and interventions to assist this population and those who interact with them.
Speakers
KS

Kia Simms

ks35047@georgiasouthern.edu, Honors College, Waters College of Health Professions
FD

Francis Desiderio

francisdesiderio@georgiasouthern.edu, Honors College
AO

Afuosino Oiboh

ao07889@georgiasouthern.edu
CB
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Cardiovascular Deaths in High-Pollution vs. Low-Pollution Areas in Georgia: A Comparative Study
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Air pollution is a growing risk factor for cardiovascular disease, yet its impact on cardiovascular mortality in Georgia remains unclear. This study examines the relationship between air quality and cardiovascular-related death rates across Georgia counties. Using Environmental Protection Agency (EPA) data, we will analyze yearly average Air Quality Index (AQI) values from 2019-2021 and compare them to age-adjusted cardiovascular mortality rates (ages 35+) from the Centers for Disease Control and Prevention (CDC). Counties will be categorized into low-, moderate-, and high-pollution groups based on AQI percentiles, and regression analyses will assess air pollution as an independent predictor of cardiovascular mortality. Adjustments will be made for demographic and socioeconomic factors, including income, smoking, obesity, and healthcare access. By mapping trends at the county level, this study aims to provide data-driven insights to inform public health policies and environmental regulations to reduce air pollution-related cardiovascular deaths in Georgia.
Speakers
SJ

Stanley Joseph

stjoseph@augusta.edu, Medical College of Georgia - Savannah Campus
CS

Christina Skariah

cjohnson1754@gmail.com, Medical College of Georgia - Savannah Campus
JS
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Characterization of Yaupon Holly root bacterial microbiome in different shade and nutrient conditions
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Yaupon Holly (Ilex vomitoria) is an overlooked plant native to Southeastern Georgia that has commercial uses like brewing tea. It is well-established that plant-microbial relationships are beneficial for plant health and resilience. Here, I will characterize the bacteria types present in Yaupon Holly roots. DNA was extracted from replicate root samples collected from 36 plants subjected to different nutrient levels and shade regimes at Temples Farm, Metter GA. From the DNA, the bacterial 16S rRNA genes were PCR amplified. Gel electrophoresis was performed to confirm the presence of bacterial DNA. Replicate PCRs from the same plant were pooled for Illumina DNA sequencing. 16S sequences will be analyzed to determine whether the bacterial composition varies with shade and nutrient levels. This will be the first study that examines the Yaupon Holly microbiome. This will provide foundational information that could lead to the development of agricultural probiotics to benefit Yaupon farmers.
Speakers
SB

Samaya Bridges

sb35946@georgiasouthern.edu, College of Science and Mathematics
JB

Jennifer Brofft Bailey

jbailey@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Cloacal bacterial microbiome characterization in nesting loggerhead sea turtles.
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Loggerhead sea turtle (Caretta caretta) hatch success (e.g., % eggs that hatch) is lower in Georgia than worldwide. Microbial infection of eggs during incubation is one threat sea turtles face. During deposition, eggs exit the mother’s cloaca, a mucus-lined orifice that also releases digestive waste. The egg surface, therefore, is coated with intestinal microbes that potentially influence egg health. Here, we seek to characterize the bacterial cloacal microbiome composition. Over 10 years, between 2013 and 2023, cloacal mucus was collected by swabbing 19 nesting loggerheads on Wassaw Island, GA. DNA was extracted from swabs and subjected to PCR targeting the V3-V4 region of the bacterial 16S rRNA gene. PCR products were subjected to Illumina-based DNA sequencing. DNA sequences will be analyzed to identify bacterial groups most frequently detected among turtles. Ultimately, this project will lead to a better understanding of the loggerhead microbiome and its contribution to egg health.
Speakers
DP

Dhruva Patel

dp14839@georgiasouthern.edu, Honors College, College of Science and Mathematics
JB

Jennifer Brofft Bailey

jbailey@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Comparing the structure, function, and stability of engineered homeodomains and natural variants
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
The improvement of stability of engineered proteins is an important area of research given the several applications of proteins that require them to be very stable. It is known that there is a generally inverse relationship between protein stability and flexibility. Proteins move around in solution and have intrinsic flexibility, which, in turn, is critical for their functionality. In this way, the relationship between stability, function, and dynamics is very complex, and the underlying principles governing this relationship are yet to be fully elucidated. Engineered, highly stable, homeodomain DNA-binding proteins have been designed to retain their functionality and, in some cases, have higher affinity to their cognate DNA partners than their natural counterparts. This project compares the stability and function of a consensus homeodomain, natural homeodomains, and rationally-designed mutants to lay the foundation for studying the complex relationship among these properties of proteins. 
Speakers
OS

Oscar Sistos Barron

os02646@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Correlation between obesity and the prevalence and management of gestational diabetes in pregnant women residing rural Southeast Georgia: a meta-analysis
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
The increasing global prevalence including overweight and obesity during pregnancy presents a significant challenge in managing both healthy pregnancy and smooth delivery. Methods: Odds ratios were used to measure (Gestational Diabetes Mellitus) GDM prevalence across BMI (Body Mass Index) categories. The researchers performed a meta-analysis to establish trends in obesity-related GDM risk such as dietary treatment, pharmacologic treatments, and lifestyle changes during pregnancy. Results: Results show a strong link between obesity and the occurrence of gestational diabetes mellitus (GDM). Metanalyses show that the chance of getting gestational diabetes mellitus (GDM) goes up significantly with higher (BMI). This supports earlier research that found that being overweight during pregnancy can lead to insulin resistance and other metabolic issues. Conclusion: Pregnant women who are at risk of obesity during pregnancy need to receive individualized interventions for weight management, to protect the health of the baby and the mother.


Speakers
TH

Taylor Holmes

th21113@georgiasouthern.edu, Jiann-Ping Hsu College of Public Health
KH

Kristina Harbaugh

kharbaugh@georgiasouthern.edu, College of Public Health
BB

Breyonna Brown

College of Public Health
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

CYBERTAP-Cybersecurity AI-Based Risk Testing & Assessment Platform
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
In penetration testing, efficiently identifying and prioritizing vulnerabilities is crucial for effective risk management. Traditional methods often rely on manual assessments or static scoring systems, which can be time-consuming and inconsistent. This research project implements an AI-driven framework that automates vulnerability prioritization and remediation recommendations, enhancing penetration testing efficiency. The system leverages data from the National Vulnerability Database (NVD), processing vulnerabilities based on their Common Vulnerability (CVE) scores and descriptions. It scans a target system and presents the user with a ranked list of the most critical vulnerabilities for immediate attention. Additionally, the tool integrates AI to provide detailed remediation guidance for each identified issue, offering actionable, context-specific advice on mitigation. This powerful dual approach accelerates decision-making, empowering security teams to swiftly neutralize the most critical threats with precision while leveraging expert-driven intelligence for maximum defense effectiveness.
Speakers
CM

Christopher Martin

cm39202@georgiasouthern.edu, Allen E. Paulson College of Engineering and Computing
FH

Felix Hamza-Lup

fhamzalup@georgiasouthern.edu, College of Engineering and Computing
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Development if nanobodies targeting the PTP from S pyogens
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)

Nanobodies (Nb) are small antigen-recognizing proteins derived from the heavy chains of camelid antibodies. They can be generated by immunization of camelids followed by isolation of competent antibodies and sequencing of the variable domain. High affinity nanobodies are then selected by ELISA or similar techniques. Another strategy is the use of synthetic libraries such as yeast surface display platforms. Using the NbLib platform, we are developing nanobodies that bind the protein tyrosine phosphatase from S. pyogenes, SP-PTP. Our strategy involves enrichment of binding-competent Nbs from the library using magnetic-activated cell sorting followed by identification of high-affinity nanobodies by ELISA. These Nbs can be used as inhibitors of SP-PTP, a virulence factor in S. pyogenes, or as tools to probe their roles inside the bacteria or host cells.
Speakers
OP

Ouedraogo Pangbewindin

po01535@georgiasouthern.edu, College of Science and Mathematics, Jack Averitt College of Graduate Studies
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Diagonising, Managing, and treating Papillary Thyroid Carcinoma through Different Imaging Modalities
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Papillary thyroid carcinoma (PTC) is the most common thyroid carcinoma. Its appearance differs depending on the variant present and the imaging modality utilized. The multiple modalities to diagnose and treat PTC, include computed tomography (CT), ultrasound (US), and nuclear medicine. A combination of imaging modalities is often used throughout the course of evaluation, treatment, and management. Ultrasound and CT are often used to aid in the diagnosis of PTC, while nuclear medicine, thermal ablation, and surgical resection are forms of treatment. Due to the many possible pathways for the combined diagnosis and treatment of PTC, additional research is required to determine the most effective imaging modality or combination of imaging modalities for PTC cases. Optimal treatment plans for different variants of PTC after initial diagnosis is another area in need of further exploration.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
RG

Rebecca Germann

rg12520@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Does size matter? Exploring how the length of the polymer polyaspartic acid influences plant growth in Arabidopsis thaliana
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Polyaspartic acid (PAA) is a biodegradable polymer synthesized from the naturally occurring amino acid, aspartate. PAA is widely used in crop production as a biostimulant, and studies have reported that it enhances plant growth and yield. However, the mechanisms of PAA mode of action, its dynamics and degradation in soil and plant systems remain poorly understood. The objective of this study is to investigate the effect of polymer size on plant growth using the model plant Arabidopsis thaliana. In addition, we will look into the dynamics of PAA in the growing media, its interaction with plant roots and how this influences plant growth. To address this objective, plants will be grown in agar-based media under sterile conditions with continuous lighting. The plants will be treated with PAA of different lengths, specifically 14,000 and 27,000 Da and growth parameters will be assessed. The expected results will provide insights into PAA’s role in nutrient acquisition and its potential applications in crop production systems.
Speakers
AL

Anne Lundy

cl19697@georgiasouthern.edu, College of Science and Mathematics
MM

Marylou Machingura

mmachingura@georgiasouthern.edu, College of Science and Mathematics
AT
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Effect of Selfie Editing on Evaluation of Natural Selfie Attractivness
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Although photo editing has been found to correlate with problematic symptoms/experiences, the lack of experimental research hinders a determination of causality. This is an experiment on the effects of selfie editing on evaluation of one’s natural appearance. Undergraduates select a task from an envelope that purportedly contains a range of aesthetic tasks. However, all participants select a task involving selfie taking. Participants rate the attractiveness of their image. Next, they are instructed in the use of FaceTune and are asked to make their image as attractive as possible and then rate its attractiveness. Participants then rate the attractiveness of a series of images in a slideshow, embedded with the unedited or edited selfie. We expect participants’ ratings of the attractiveness of their unedited selfie will decrease after selfie editing. If photo editing causes a decreased appreciation for one’s natural appearance, there is a potential pathway to more lasting effects of appearance dissatisfaction such as seeking of cosmetic procedures. 
Speakers
JR

Joshua Richardson

jr32847@georgiasouthern.edu, College of Behavioral and Social Science
PK

Pamela Kplivi

pk03886@georgiasouthern.edu, College of Behavioral and Social Science
ND

Nicholas Dillard

nd05667@georgiasouthern.edu, College of Behavioral and Social Science
WW

Wendy Wolfe

wlwolfe@georgiasouthern.edu, College of Behavioral and Social Science
CS

Caden Stalnaker

College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Enzymatic activity and inhibitation of S Pyogenes protein tyrosine phospahte
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
The protein tyrosine phosphatase from Streptococcus pyogenes, SP-PTP, is an important regulatory protein in this human pathogen. Studies have shown that SP-PTP regulates as much as 50% of genes involved in virulence of S. pyogenes. Because of this, it is important to study its function and interaction with potential inhibitors. Recombinant SP-PTP was expressed in E. coli and purified through affinity and size exclusion chromatography. The phosphatase activity was characterized using a synthetic substrate, para-nitrophenylphosphate. Kinetics parameters were determined by monitoring the production of dephosphorylated substrate. Inhibition by known protein tyrosine phosphatase, sodium orthovanadate, was also characterized. SP-PTP shares a very similar structure with the human low molecular weight protein tyrosine phosphatase, LMW-PTP. As only the open conformations of both are currently available, a vanadate-bound structure will reveal more about the mechanisms of both proteins. Finally, LMW-PTP inhibitors will also be characterized for their potential ability to inhibit SP-PTP.
Speakers
ND

Nicholas Dillon

nd05754@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Evaluating the Efficacy of TAGteach: A Systematic Review
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
TAGteach (Teaching with Acoustical Guidance) is an instructional technology that provides learners with immediate feedback to reinforce correct responses during skill acquisition. TAGteach relies on use of an acoustical marker (e.g., a click sound) to signal correct behavior, thereby minimizing or eliminating the need for verbal feedback. By presenting a distinct auditory stimulus to act as a marker, instructors can provide precise and immediate feedback on specific skill components. The purpose of this literature review included systematically examining the existing research on the use of TAGteach for acquiring novel behaviors and skills. We evaluated its effectiveness as an intervention by calculating Tau-U effect sizes and summarized key descriptive variables. Further, we analyzed procedural variations across studies to identify any commonalities and differences in TAGteach implementation. This poster will highlight findings from the review and discuss recommendations for practice/future research. 
Speakers
DD

Devon Dashnaw

dd13957@georgiasouthern.edu, College of Behavioral and Social Science
JW

Jennifer Wertalik

jwertalik@georgiasouthern.edu, College of Behavioral and Social Science
TF
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Evaluating the Impact of TAGteach Verbal Cues on Origami Skill Acquisition in College Students
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
TAGteach (Teaching with Acoustical Guidance) represents an intervention package that has been found effective for the development of skills in areas such as dance, golf, yoga, and surgical skills. TAGteach simplifies the targeted skill into several steps, called tag points. The instructor states the tagpoint to the learner (e.g., the tagpoint is…) and marks correct responses using an acoustical stimulus that produces a “click” sound. Given that TAGteach represents an intervention package with multiple components, it is unknown whether its effectiveness lies in the complete package or if variations of its components are sufficient for skill acquisition. Therefore, the purpose of the present study was to compare two different variations of the TAGteach intervention by teaching college students how to make origami figures. We aimed to investigate the effects of using the verbal cue (e.g., the tagpoint is…). Findings and implications for practice will be presented.
Speakers
AG

Alexis Golden

ag29197@georgiasouthern.edu, College of Behavioral and Social Science
JW

Jennifer Wertalik

jwertalik@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Evaluation of Impulsivity as a Predictive Behavioral Marker for Treatment Relapse in Children with Developmental Disabilities
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Resurgence refers to the reemergence of destructive behaviors after an intervention, particularly when an alternative response, learned during treatment, is exposed to worsening conditions. Identifying predictive variables for resurgence, such as impulsivity, is key to reducing its impact. Impulsivity involves choosing smaller, immediate rewards over larger, delayed ones. Understanding impulsivity’s role in resurgence may guide more effective interventions. This study examined the sensitivity and specificity of a modified Progressive Interval Assessment (PIA) for measuring impulsivity in individuals with developmental disabilities exhibiting problem behaviors. Researchers assessed participants' sensitivity to varying rewards to develop the modified PIA, identifying the breakpoint at which individuals reverted to problem behavior after delays in receiving larger rewards. These breakpoints were examined for their predictive value for resurgence during Functional Communication Training (FCT), which teaches alternative communication responses. A second modified PIA assessed shifts in impulsivity following FCT, contributing to a better understanding of impulsivity as a behavioral marker for resurgence.
Speakers
avatar for Kayla Randall

Kayla Randall

krandall@georgiasouthern.edu, College of Behavioral and Social Science
Dr. Randall is a Board Certified Behavior Analyst at the doctoral level and Assistant Professor at Georgia Southern University. She earned a Master’s of Education degree in Special Education from Vanderbilt University. She earned a doctoral degree in Applied Behavior Analysis from... Read More →
AB

Amanda Bradley

ab40952@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Experience, Perception, and Application of Extinction: Procedures in Behavioral Health Treatments
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Procedural extinction in the context of behavioral interventions directly refers to the reduction of problematic behavior. This is achieved by withholding or stopping the reinforcement that the participant’s problem behavior is contingent upon (Iwata et al., 1994). Although there has been research evaluating procedural extinction’s effectiveness and ways to mitigate its known side effects, there is limited research on the social validity of the intervention and how this impacts its application. In the current study, we inquired about clinicians’ experience, perception, and application of extinction across behavioral health settings. This was done initially by replicating and extending survey instruments and procedures to accurately gather data from responding clinicians (Roscoe et al.). In addition, we asked the survey pool and a wider audience to participate in a choice-based task to determine the likelihood of selecting an extinction behavior reduction intervention versus a non-extinction-based reduction intervention with delays to efficacy. 
Speakers
avatar for Kayla Randall

Kayla Randall

krandall@georgiasouthern.edu, College of Behavioral and Social Science
Dr. Randall is a Board Certified Behavior Analyst at the doctoral level and Assistant Professor at Georgia Southern University. She earned a Master’s of Education degree in Special Education from Vanderbilt University. She earned a doctoral degree in Applied Behavior Analysis from... Read More →
GH

Gabrielle Harris

gh07513@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

FCT Literature Review
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Functional communication training (FCT) is a function based intervention which increases communication responses that functionally replace abhorrent behaviors. The intervention utilizes differential reinforcement of alternative response procedures to establish alternative responses as a treatment for severe problem behaviors. FCT can involve a variety of communication topographies, and has been implemented with individuals diagnosed with various developmental disabilities. FCT pre-training, the initial training phase, involves placing abhorrent behavior on extinction while using various prompting methods to establish the functional communication response (FCR) in the individual’s repertoire. Establishment of the FCR in the initial phase is critical for response generalization, and maintenance. In a systematic review of behavior analytic literature FCT is commonly used as an alternative response intervention, however much of the literature does not sufficiently report on FCT Pre-training. Literature review findings, implications for future research, and grounds for future research are to be discussed.
Speakers
avatar for Kayla Randall

Kayla Randall

krandall@georgiasouthern.edu, College of Behavioral and Social Science
Dr. Randall is a Board Certified Behavior Analyst at the doctoral level and Assistant Professor at Georgia Southern University. She earned a Master’s of Education degree in Special Education from Vanderbilt University. She earned a doctoral degree in Applied Behavior Analysis from... Read More →
VG

Victoria Grim

vg00838@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Filter Folies: The Art of Over-Editing
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Social networking sites (SNS) like Instagram, Facebook, and Twitter have been integrated into Americans' lives and facilitated social engagement, leading to self-presentation effects where individuals emphasize desirable versions of themselves. The rise of photo editing applications reflect this desire for ideal self-representation. McGovern et al. (2022) highlighted the need to study the effects of social media usage and photo editing on identity and self-image, suggesting research be conducted on the relationship between photo investment, manipulation behaviors, and variables like appearance dissatisfaction, body surveillance, and perfectionism. This study utilized a revised Self-Photo Manipulation Scale to explore correlations between various editing behaviors and potential correlates, including concerns about body size and facial appearance. Findings are expected to reveal significant gender differences and also relationships between photo investment and editing and issues such as body surveillance, physical appearance comparisons and dissatisfaction, and perfectionism, ultimately aiding in developing effective interventions for photo editing behaviors.
Speakers
JR

Joshua Richardson

jr32847@georgiasouthern.edu, College of Behavioral and Social Science
PK

Pamela Kplivi

pk03886@georgiasouthern.edu, College of Behavioral and Social Science
WW

Wendy Wolfe

wlwolfe@georgiasouthern.edu, College of Behavioral and Social Science
TS
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Finding Common Ground: How Demographics and Communication Shape ENT Relationships and Advisement
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Despite studies showing the benefits to mentored trainees, particularly women, minorities, and non-traditional students often find their voices overlooked in larger student bodies, and their specific needs are not always addressed by traditional programs, limiting their full potential. This has contributed to their underrepresentation in surgical specialties, especially otolaryngology (ENT). This study is survey and interview-based, involving residents and faculty across various otolaryngology programs, in which their responses will be analyzed to identify patterns that define valuable mentorship experiences. Five preliminary themes have emerged, with "Communication," "Connection Outside the Workplace," and "Similarities Matter but Aren't Everything" being the most recurring and impactful. All participants shared that they were both informal mentors and mentees, and they emphasized the value of mentorship in both their personal and academic life at all stages.
Speakers
KM

Kiran Manocha

kmanocha@augusta.edu, Medical College of Georgia - Savannah Campus
HK

Heather Koehn

hkoehn@augusta.edu, Medical College of Georgia - Savannah Campus
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Grieving Unequally: How Social Factors Impact Adolescent Parental Loss
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Losing a parent during adolescence is an emotional experience shaped by social factors like family support, community resources, and financial stability. Adolescence is already a time of major change, and parental loss can increase the risk of depression, anxiety, and academic struggles. However, not all teens experience grief in the same way. Access to financial and emotional resources, such as supportive families, schools, and communities, may help adolescents cope better. Teens in under-resourced areas often struggle due to fewer financial resources and trouble accessing mental health care. Grief is not just a personal struggle; this literature review examines the social factors influencing grieving and healing. Improving access to resources can help ensure that all grieving adolescents receive the support they need.
Speakers
JR

Jazmine Roberts

jr29786@georgiasouthern.edu, College of Behavioral and Social Science
SA

Schueths April

aschueths@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

How zonation patterns in salt marsh habitats affect diversity of terrestrial arthropods
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
This study investigates how intertidal Spartina alterniflora terrestrial arthropods community diversity changes with zonation from the terrestrial saltmarsh edge to the aquatic edge. There will be three 10-meter transects at both sites (Butterbean Beach and Priest Landing) running parallel to the water line: one in the middle of the Spartina patch, one on the higher edge of the patch as it transitions into a terrestrial habitat, and one on the lower edge of the Spartina patch which transitions into an aquatic habitat. Specimens will be sampled along these transects twice using sweep-nets at low tide, and weather conditions (temperature, clouds, wind) will be measured to try and keep conditions consistent between samples. The specimens will be used to measure species richness, abundance, and diversity between transects and sites.
Speakers
DO

Dominick Oursler

do03473@georgiasouthern.edu, College of Science and Mathematics
JZ

Jennifer Zettler

Mentor, College of Science and Mathematics
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

10:00am EDT

Investigating the Efficacy of TAGTeach to Teach Yoga Among College Students
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
Recent data suggests a concerning increase in mental health challenges among college students. Untreated mental health conditions can have significant negative consequences on college students’ lives such as poor academic performance, hindered social relationships, reduced quality of life, and increased risk of substance abuse. Yoga may offer a potential option to help tackle mental health problems among college students. TAGteach (Teaching with Acoustical Guidance) offers an intervention package that has been shown to improve performance in areas of sports and athletic activities. The current study systematically replicated Ennett and colleagues (2020) by examining the effects of TAGteach to teach beginner yoga poses to college students. We compared two error-correction procedures: standard TAGteach and TAGteach with reduced practice, to assess the impact on skill acquisition, maintenance, and generalization. This presentation will discuss results and provide practical recommendations for applying TAGteach within health and wellness programs, as well as provide directions for future research.
Speakers
KW

Kaitlyn Wyllie

kw13370@georgiasouthern.edu, College of Behavioral and Social Science
JW

Jennifer Wertalik

jwertalik@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 10:00am - 12:00pm EDT
Savannah Ballroom (211A)
  Poster Presentation

1:15pm EDT

Comparative Analysis of Deterministic and Stochastic SIR Models in Modeling Measles Epidemics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
This study investigates the dynamics of measles epidemics using deterministic and stochastic SIR models. In the deterministic model, we analyze infection dynamics through the basic reproductive number  \({\mathcal{R}_0} \),  assessing equilibrium stability for \(\mathcal{R}_0 < 1 \) and \(\mathcal{R}_0 > 1 \).  In the stochastic model, we establish the existence of global solutions and define the stochastic reproductive number \({\mathcal{R}^s_0}\),  examining disease dynamics under varying environmental fluctuations. While the deterministic model suggests disease persistence, stochastic factors introduce the possibility of extinction events, highlighting the impact of randomness on disease transmission. Additionally, we present conditions for infection extinction and discuss the stochastic stability of solutions. Numerical simulations illustrate the theoretical findings. 
Speakers
MH

Minh Ha

mh34830@georgiasouthern.edu, College of Science and Mathematics
DD

Dawit Denu

ddenu@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Implementation of an Evidence-Based Behavioral Health Crisis Management Algorithm in a Pediatric Emergency Department
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Effective behavioral crisis management is essential for patient and staff safety in healthcare settings. Although physical restraints are commonly used in acute care facilities, they present significant risks of harm and psychological trauma. This study assessed the impact of implementing a behavioral crisis management algorithm, combined with an educational component, on reducing restraint use in a pediatric emergency department. A quality improvement initiative was conducted across three pediatric emergency sites within one hospital system in the Southeastern U.S. This project examined restraint utilization three months before and after implementation of the algorithm. Forty-five emergency department clinicians participated in a structured one-hour training session on the use of the crisis management algorithm. Pre-intervention data indicated that many providers felt inadequately prepared to manage behavioral crises and were unfamiliar with existing crisis management guidelines. The use of physical restraints before the intervention was significantly high, around 73.25%.  Post-intervention findings demonstrated a decrease in restraint use to approximately 46.15%,  representing a 27% reduction in restraint utilization. Additionally, staff reported a 16% increase in competency and comfortability in using the algorithm, along with a 74% improvement in adherence to the crisis management protocol. These findings highlight the importance of  structured protocols and competency-based training in minimizing restraint reliance. Future research should explore long-term outcomes and scalability of similar interventions in diverse healthcare settings.
Speakers
TW

Tori Watson

tw18413@georgiasouthern.edu, Waters College of Health Professions
ES

Elizabeth Snyder

esnyder@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Incorporation of Spin Labels to Study the Structure and Conformation of Human Guanylate Kinase
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Enzymes are proteins that catalyze a biological reaction. During catalytisis, enzymes undergo conformational changes accommodating substrate binding and product release. GMPK catalyzes the conversion of GMP and ATP to GDP and ADP. GMPK typically assumes an open U-shaped conformation. Upon binding of the substrates, GMP and ATP, its lid domain locks the substrates in place adopting a closed conformation. This open/closed transition has been detected by SAXS and AUC in human GMPK and by X-ray crystallography for homologs. We are interested in studying the dynamics of this transition using biophysical techniques such as electron paramagnetic resonance and paramagnetic relaxation enhancement NMR. To accomplish this, we first need to generate spin labelled versions of GMPK. Spin labelled will be introduced site-specifically by cysteine reactivity, using MTSL, in a cysless GMPK background. SDSL combined with EPR and PRE will allow for characterization of the dynamics of GMPK in solution.
Speakers
KV

Kaitlyn van Ostenbridge

kv04265@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Intelligent Virtual Human Assistants (INTEL-VHA)
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Virtual Human Assistants (VHAs) represent a groundbreaking evolution in digital interaction, seamlessly blending advanced natural language processing, expressive facial animations, and lifelike gestures to create immersive, human-like experiences. This study delves into the transformative impact of VHAs on user engagement and learning outcomes by integrating cutting-edge audio-visual elements. Participants will experience three distinct lecture formats: (1) audio-only, (2) audio paired with a VHA face, and (3) audio enhanced by a fully expressive VHA with dynamic facial expressions and body movements. To maximize interactivity and immersion, each lecture incorporates gamified elements, such as real-time, adaptive questioning. Ensuring consistency across all formats, we employ MetaHuman technology within Unreal Engine, delivering realistic, uniform VHAs for a controlled study environment. By fusing VHAs with gamification, this research aims to uncover the optimal synergy of audio and visual stimuli that drives deeper learning, enhances user experience, and reshapes the future of digital education.
Speakers
JV

Jocelyn Varghese

jv06042-sw@georgiasouthern.edu, Allen E. Paulson College of Engineering and Computing
FH

Felix Hamza-Lup

fhamzalup@georgiasouthern.edu, College of Engineering and Computing
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Introducing: The D4N+, A Collaborative Network to Strengthen Biomedical Research at Georgia Southern
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
To accelerate the discovery and development of therapeutic molecules and biological evaluation, we propose the D4N+ (Network for Data, Discovery, and Drug Design). This collaborative network will enhance synthesis and biomedical research at Georgia Southern University by supporting investigators with a shared goal of developing and promoting potential therapeutics. Through collective efforts, the center aims to expedite the transition from "beaker to bench" and ultimately from "bench to bedside." This initiative will foster a collaborative and interdisciplinary environment within the College of Science and Mathematics at Georgia Southern University and with regional partner institutions.
Speakers
avatar for Shainaz Landge

Shainaz Landge

slandge@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
RK

Rebecca Kocerha

College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Investigations in Optimal Eurymerodesmus varius Captivity Care For Study of Gregarine Parasites: A Case Study
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Eurymerodesmus varius is a species of flat-back millipede with a range that expands across the Southeastern United States. While commonly encountered, Eurymerodesmus are relatively small and thus are overlooked and understudied. In fall of 2023, millipedes were found crawling into buildings on Georgia Southern University’s Armstrong Campus in Savannah and dying en masse. Because parasites are known to elicit behavioral responses in some infected hosts, we dissected the dying millipedes and surveyed them for nematodes and other potential parasites. We found a high (>65%) prevalence of gregarine Apicomplexans within the intestines and body cavity of male and female millipedes. While gregarines are often considered to be parasites that can cause behavioral modifications in their hosts, they can also form commensalistic or mutualistic partnerships. We determined the presence, abundance, and types of gregarines found in both dying and healthy E. varius specimens
Speakers
RR

Reagan Reese

rr13515@georgiasouthern.edu, College of Science and Mathematics
JZ

Jennifer Zettler

Mentor, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Investigations in Patterns of Gregarine Parasitism in Flat Back Millipedes Exhibiting Mass Migrations
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Eurymerodesmus varius is a species of flat-back millipede with a range that expands across the Southeastern United States. While commonly encountered, Eurymerodesmus are relatively small and thus are overlooked and understudied. In fall of 2023, millipedes were found crawling into buildings on Georgia Southern University’s Armstrong Campus in Savannah and dying en masse. Because parasites are known to elicit behavioral responses in some infected hosts, we dissected the dying millipedes and surveyed them for nematodes and other potential parasites. We found a high (>65%) prevalence of gregarine Apicomplexans within the intestines and body cavity of male and female millipedes. While gregarines are often considered to be parasites that can cause behavioral modifications in their hosts, they can also form commensalistic or mutualistic partnerships. We determined the presence, abundance, and types of gregarines found in both dying and healthy E. varius specimens
Speakers
RR

Reagan Reese

rr13515@georgiasouthern.edu, College of Science and Mathematics
JZ

Jennifer Zettler

Mentor, College of Science and Mathematics
MS
P
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Is Nothopassalora personata, the causal agent of Late Leaf Spot of Peanut, reproducing sexually in GA peanut fields?
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Late leaf spot (LLS) of peanut, caused by the fungus Nothopassalora personata, causes leaf defoliation, and even death in peanut plants, reducing crop yields and costing an average of $44 million losses per year. The fungus can be chemically controlled by fungicides; however, it is likely that the fungal pathogen has evolved the ability to avoid negative effects of these chemicals. Evolution of fungi occurs through reproduction. Fungi reproduction include asexual, where fungi produce genetically-identical spores, and sexual, where opposite mating types contribute DNA and produce genetically-unique spores which lead to genetic diversity in fungal populations. Our research question is: Is Nothopassalora personata reproducing sexually in GA peanut fields? We collected LLS samples, extracted DNA, and tested that DNA for the presence of two mating genes: MAT-1 or MAT-2. Results indicate that both mating types are present in the same peanut field in south GA; therefore, sexual reproduction is possible.
Speakers
SG

Sara Gremillion

sgremillion@georgiasouthern.edu, College of Science and Mathematics
SB

Sarah Beriault

sb39169@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Measuring local law enforcement's perception of ICE Interventions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Following the 2025 Presidential Inauguration, new federal immigration policies have been enacted that may impact local law enforcement. Prior research suggests that negative media portrayals of police influence law enforcement self-legitimacy. Accordingly, public perceptions of these policy changes may similarly affect local agencies. This study examines local law enforcement attitudes toward ICE oversight, the extent of their cooperation with federal mandates, and the perceived impact of such interventions on community relations, crime reporting, and officer self-legitimacy. A survey will assess perspectives on ICE involvement, federal-local collaboration, and its effects on public trust and policing efficacy. We hypothesize that many agencies will express reluctance toward extensive ICE intervention, citing concerns over strained community relations, resource allocation, and the erosion of local policing priorities. The study will discuss the broader implications of these findings for law enforcement and policymaking.
Speakers
avatar for Jeremiah Davallou

Jeremiah Davallou

jd36995@georgiasouthern.edu, College of Behavioral and Social Science
AL

Ashley Lockwood

alockwood@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Pediatric Spinal Dysraphism: A Comparative Analysis of Ultrasound and MRI for Diagnosis and Management
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Pediatric spinal dysraphism is a congenital condition that results from the neural tube failing to fuse correctly, resulting in spinal deformation and other anomalies including spina bifida, meningocele, and myelomeningocele. This condition is uncommon, occurring in about 1 in 1,000 live births, and is most often diagnosed in newborns or infants. Diagnostic imaging modalities such as ultrasound and magnetic resonance imaging (MRI) are commonly employed to assist in the diagnosis and treatment of pediatric spinal dysraphism. Ultrasound is a popular technique for its lack of ionizing radiation and its effectiveness in early diagnosis. Ultrasound is also considered the most accessible imaging modality. MRI is renowned for its ability to produce high-resolution images of the spinal cord, allowing easy identification of spinal inconsistencies or pathology. Many professionals in the field of radiologic sciences have claimed these modalities to be complementary to each other, each one having its advantages to contribute to diagnostic accuracy and efficacy. However, some studies still strive to reinforce the use of ultrasonic technology as the gold standard. The purpose of this comparative research analysis is to determine and assess the correlations, advantages, and disadvantages of different imaging modalities to determine which technique offers superior diagnostic accuracy and efficacy for the early detection, diagnosis, and management of pediatric spinal dysraphism. By establishing a standardized diagnostic approach that maximizes the advantages of both modalities, professionals will be better equipped to enhance clinical decision-making and improve patient outcomes in this at-risk population.This collaborative effort ensures accuracy and efficiency in early detection, assists with a time-based course of action, and improves foreseeable outcomes for children with this condition. The established goals for future collaboration and continued research include advancing diagnostic technology, improving imaging protocols and standards, and making continuous advancements in interdisciplinary integration and pediatric care standards.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
JD

Julianna Dine

jd29412@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Politics in Every Strand: Exploring Black Men and Women’s Perspectives on the Politicization and Criminalization of Black Hair
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
This research project explored Black men and women’s perspectives on the politicization and criminalization of Black hair, giving attention to the ways in which  societal, cultural, and political factors shape their experiences and perceptions. Data for the current study was gathered  using semi-structured interviews with a diverse group of Black individuals.  Participants are asked to elaborate on how they understand Black hair as an expression of both resistance and conformity in various social contexts. Participants shared information about personal emotions, perspectives, and experiences with their hair, as well as the impact of racialized beauty standards and political movements (such as the Natural Hair Movement) have influenced their own hair choices. This study aims to contribute to a deeper understanding of the intersection of race, gender, cultural identity, and beauty standards; as well as to shed light on how Black individuals negotiate and navigate the political, social, and cultural complexities surrounding their hair.
Keywords: Race, Politics, Hair, Resistance, Criminalization
Speakers
AS

Anaya Smith

as45737@georgiasouthern.edu, College of Behavioral and Social Science
AD

Akiv Dawson

adawson@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Polyaspartic Acid: A Promising Biostimulant for Sustainable Agriculture
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
The widespread use of harmful pesticides to boost crop yield is common in modern agriculture. However, biostimulants offer an eco-friendly alternative that can reduce reliance on chemical fertilizers. Amino acid-based biostimulants are particularly promising due to their biodegradability and positive impact on plant growth. Polyaspartic acid (PAA) is an example of this type of additive that has been shown to retain/improve crop parameters at lowered nutrient levels. Our part in this collaborative project is to track and quantify PAA in plant growth media (agar gel) using spectroscopic techniques (UV-vis, fluorescence, etc.). Reported here is our initial methodology for performing these measurements and our steps to optimize the process into an efficient and reproducible protocol. Ultimately, understanding PAA’s influence on nutrient absorption, this research aims to contribute to the development of sustainable agricultural practices.
Speakers
avatar for Shivam Patel

Shivam Patel

sp21138@georgiasouthern.edu, College of Science and Mathematics
NS

Nathaniel Shank

nshank@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Reinforcer Quality Degradation and Resurgence without Extinction: Effects on Operant Behavior
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
In the treatment of problem behavior, practitioners aim to reduce the frequency of a specific response by differentially reinforcing a socially desirable alternative behavior while withholding reinforcement for the problem behavior, thereby placing it on extinction. Under these conditions, resurgence may occur, in which a previously extinguished response reemerges following the discontinuation of reinforcement for a more recently reinforced alternative behavior due to changes in reinforcement conditions or schedules. As an alternative to the immediate withdrawal of reinforcement (i.e., extinction), gradual degradation of reinforcer quality may also reduce problem behavior by progressively reducing the value of reinforcement across trials, leading to a gradual reduction in responding to a desirable level. This study investigates how reinforcer quality affects the level of resurgence, in a controlled laboratory setting using Long-Evans rats. 
Speakers
avatar for Kayla Randall

Kayla Randall

krandall@georgiasouthern.edu, College of Behavioral and Social Science
Dr. Randall is a Board Certified Behavior Analyst at the doctoral level and Assistant Professor at Georgia Southern University. She earned a Master’s of Education degree in Special Education from Vanderbilt University. She earned a doctoral degree in Applied Behavior Analysis from... Read More →
DD

Devon Dashnaw

dd13957@georgiasouthern.edu, College of Behavioral and Social Science
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Scroll, Stalk, and Vote: The Surprising New Age of Political Engagement
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Parasocial relationships (PSR’s) are one-way relationships that are formed between an individual and a media figure. Individuals can develop a strong sense of familiarity, kinship, and connection with these idols, even with a lack of reciprocity. PSRs may have an impact on one’s emotional well-being, identity formation, and even consumer or voting behavior. Data was collected from participants in Psychology and Political science classes via an online survey. The participants responded to the Multidimensional Measure of Parasocial Relationships (MMPR). The MMPR was an 18-item scale that evaluated participants' thoughts, feelings, and behaviors regarding their parasocial relationships with social media figures. They also responded to several research-designed questions that assessed admiration and interest in politicians and politics. This study aims to build upon emerging research by investigating the relationship between PSRs and interest in politics, preference for social media platforms, and choice of virtual engagement strategies. 
Speakers
JE

Jonathan E. Roberts

jeroberts@georgiasouthern.edu, College of Behavioral and Social Science
JR

Joshua Richardson

jr32847@georgiasouthern.edu, College of Behavioral and Social Science
CS

Caden Stalnaker

College of Behavioral and Social Science
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Sexual Violence Leading to Movements: A World Wide Phenomenon
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Millions of women have experienced sexual violence in their lives. These sexual violence cases have led to different scales of movements worldwide. From the Reclaim the Night movement of the 1970s to more recent movements such as the MeToo and Nirbhaya movements. In previous research, it has shown that when women break the silence and stigma of sexual violence, more women feel inclined to do the same. Using data from the American Journal of Preventive Medicine, the survivors of sexual assault know their assailants. Leading to many social factors keeping them from sharing with people who have harmed them sexually. Fortunately, with these recent movements appearing, more women have felt a sense of empowerment to share their stories or fight for women who have decided to share their stories.   
Speakers
avatar for Nalanda Roy

Nalanda Roy

nroy@georgiasouthern.edu, College of Behavioral and Social Science
TM

Timiyah McIntosh

tm26509@georgiasouthern.edu, Honors College, College of Behavioral and Social Science
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

So Many Ways to Create a Good Selfie
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
With the rise of AI-powered photo editing tools and the sharing of highly edited photos across social media, concerns about the impact of selfie photo editing have grown. Our initial 2023 study addressed outdated measures of photo taking and editing behaviors. Survey responses from 120 female college students using the Self Photo Manipulation Scale (SPMS-r) and the Photo Investment Scale (PIS-r) were analyzed using exploratory factor analyses. Factor analysis of the SPMS-r identified three components—Editing Facial Features, General Editing, and Editing Body Features. However, the PIS-r analysis revealed unclear constructs and low internal consistency. This study aims to validate and refine these findings by readministering the survey to additional participants to re-examine scale reliability and also to examine concurrent validity with measures of related constructs. The goal is to create current, psychometrically sound measures of photo taking and editing in order to advance insights into photo-related behaviors and effects.
Speakers
ND

Nicholas Dillard

nd05667@georgiasouthern.edu, College of Behavioral and Social Science
WW

Wendy Wolfe

wlwolfe@georgiasouthern.edu, College of Behavioral and Social Science
AJ
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Structural and functional characterization of a putative algal bicarbonate transporter, CIA8, in Escherichia coli
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
The carbon dioxide concentrating mechanism (CCM) in the green alga Chlamydomonas reinhardtii is essential for photosynthesis, and inducible under CO2-limiting conditions. The key components of the CCM are transport proteins, which allow passage of bicarbonate across various cellular membranes. This study focuses on the CIA8 protein, a putative inorganic carbon transporter localized to the chloroplast membrane. The structure and mechanism of CIA8 function in Chlamydomonas are not yet known. Our objective is to characterize CIA8, elucidate its structure and mode of function. To support our goal of characterizing the structure of CIA8, we will recombinantly express it in E. coli using the T7 Expression strain. Meanwhile, we will use a carbonic anhydrase (CA) mutant of E. coli to evaluate the ability of CIA8 to complement the loss of function of CA. The mutant does not grow well in limiting CO2 conditions which we can take advantage of to evaluate if CIA8 is functional in E. coli. Results will provide insights into the 3D structure and role of CIA8 in Ci uptake and its potential application in improving photosynthesis in food crops.
Speakers
BC

Barbara Comer

bc15424@georgiasouthern.edu, College of Science and Mathematics
MM

Marylou Machingura

mmachingura@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Differential Role of Mammography and Sonography in Detecting Breast Cancer
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Breast cancer is the most common malignancy and cause of cancer-related death in women globally. Early detection is vital for improving survival and treatment options. This study compares the effectiveness of mammography and sonography in detecting breast cancer. Women are advised to begin annual mammograms at age 40, unless there is a family history of breast cancer. Sonography is often used when mammograms show abnormalities, women with dense breast tissue, during pregnancy, or when a palpable mass is detected. While mammography is widely used, it may not always be available or feasible in some settings. Sonography, alone or combined with mammography, can also be effective. Studies show that depending on factors like age, breast density, and family history, sonography may have higher sensitivity than mammography. The combination of methods offers superior diagnostic accuracy, suggesting that integrating sonography with mammography could enhance breast cancer detection, especially in patients with dense tissue.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
AS

Alexandra Strain

as42356@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Effects of Magnetic Resonance guided Focused Ultrasound on Uterine Fibroids
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Magnetic Resonance (MR) guided focused ultrasound (gFUS) is a relatively new minimally invasive technique that uses high-intensity focused ultrasound (HIFU) guided by magnetic resonance (MR), also known as MRgFUS, to treat several diseases, such as prostate cancer, breast cancer, and particularly uterine fibroids. Uterine fibroids (UFs), also known as leiomyomas, are non-cancerous tumors that grow in or around the uterus. They are the leading cause of hysterectomies, which are currently the most accepted treatment option. The aim of this research is to determine the effects of MRgFUS treatment on symptomatic uterine fibroids. The MRgFUS technology uses ultrasound and MRI simultaneously. The combination of these two modalities operates by using focused thermal ablation via ultrasound and MRI to precisely guide and target the lesions. In more detail, when ultrasound, or more specifically FUS, travels through the body, it results in molecular rearrangement leading to tissue heating, which causes thermal ablation. MR, moreover, has the ability to map the temperature elevation of the focal spot and surrounding tissues, resulting in superb precision and accurate monitoring of organ motion. Therefore, ultrasound and magnetic resonance imaging collaborate to enable safe and controlled non-invasive heat ablation for uterine fibroids. Future goals to possibly be explored with the connections of my findings is the use of this technology with larger size UF’s and women wanting to conceive. This research aims to provide a new minimally invasive approach that may offer an alternative treatment for women with uterine fibroids. Additionally, the research will facilitate the discovery of the advantages, limitations, and postoperative effects of the MRgFUS treatment.


Keywords: MRgFUS, HIFU, uterine fibroids, leiomyomas
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
KP

Kennedi Porcher

kp17026@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Role and Importance of Lung Ultrasound and its Uprising Collaboration with Respiratory Therapists
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Lung ultrasound (LUS) is making an emergence as an essential diagnostic tool in respiratory critical care medicine. LUS offers a simple, rapid, beside approach for evaluating, diagnosing, and treating pulmonary related diseases and conditions such as pleural effusion, pneumonia, pneumothorax, and COVID-19 associated lung injury. Unlike other modalities such as computed tomography (CT) and X-ray, LUS offers a non-invasive approach by having the advantage of the absence of radiation exposure. It is a diagnostic tool that is being integrated into respiratory therapy practice to enhance respiratory care, causing a collaboration between ultrasound technicians and respiratory therapists (RTs). This research aims to examine the role and importance of lung ultrasound in respiratory care and diagnosis and the collaborative training provided by ultrasound technicians to equip RTs with LUS skills. There have been multiple comprehensive literature reviews conducted to analyze studies on the application of LUS in diagnosing and treating pulmonary diseases. Within these studies, there has been mention of the collaborative efforts between ultrasound technicians and respiratory therapists to enhance diagnostic capabilities and improve patient care outcomes by using LUS. This research aims to examine both previously mentioned statements by going in depth about each listed concept. Future goals that can possibly be explored to further improve research between the collaboration of these two modalities are those such as developing and implementing standardized training LUS protocols for RTs, and establishing continuous education workshops where ultrasound technicians and RTs can share knowledge, skills, and information about the latest advancements in LUS technology and practices.
Keywords: Lung ultrasound, pneumothorax, pleural effusion, pneumonia, respiratory
therapists, collaborative efforts
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
YP

Yesenia Pardo

yp00811@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Role of A Generalized Identity Matching Repertoire on the Emergence of Symmetry Using Olfactory Stimuli with Rats
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
This project will extend current literature in stimulus equivalence in rats using olfactory stimuli (i.e., odors in the form of essential oils). More specifically, we want to determine if using olfactory stimuli in a match-to-sample task will replicate the paucity of previous research which suggests that rats may have the ability to demonstrate transitivity.
Speakers
AB

Amanda Bradley

ab40952@georgiasouthern.edu, College of Behavioral and Social Science
AB

Andrew Bulla

abulla@georgiasouthern.edu, College of Behavioral and Social Science
JF
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Role of Diagnostic Ultrasound and CT in Image-Guided Liver Biopsies
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
A liver biopsy can be a vital resource for diagnosing, assessing, and treating a variety of liver
diseases and conditions. A liver biopsy is conducted by taking a sample of liver tissue by way of
a needle that is then taken to a laboratory for testing. This can be performed in a variety of ways.
The gold standard for liver biopsies is performing them under image guidance. The two most
common imaging modalities used are ultrasound and computed tomography (CT). Within each
of these modalities, liver biopsies can be performed in multiple ways. CT-guided biopsies can be
performed unenhanced, intravenous (IV) enhanced, and intra-arterial Lipiodol-marked enhanced.
Ultrasound biopsies can be performed percutaneously with either no contrast or with contrast and
can also be performed endoscopically (EUS). When a liver biopsy is performed it is either
targeted or random. Indications for a targeted liver biopsy include to differentiate between benign
and malignant, primary or secondary malignancy, or to diagnose or stage metastatic disease.
Random liver biopsy indications include acute injury, chronic parenchymal disease, transplant
rejection, and abnormal liver function tests. Risks associated with liver biopsies include pain,
bleeding, injury to other structures, allergic reactions, bile leaks, and death. Using ultrasound is
considered the gold standard for image guided liver biopsies, but in some cases CT guidance
should be used. These instances include when lesions are not adequately visualized on ultrasound
or when a safe needle trajectory can’t be identified with ultrasound. This research aims to
compare the use of ultrasound and CT for image guided liver biopsies and the different types
used for each, as well as understanding the safety of image guided liver biopsies and emerging
technology. Continued research should be conducted involving endoscopic ultrasound guided
liver biopsies and contrast use in image guided biopsies to understand their significance.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
ST

Savannah Thomason

st14389@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The role of salt marsh microbes and chemical compounds on seed development and germination in Spartina alterniflora
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Recent research has focused on seed propagation methods for the salt marsh plant Spartina alterniflora to support marsh restoration initiatives. This study examined the role of salt marsh microbes and chemical compounds on seed development and germination through two experiments. The first investigated the role of microbes and chemical compounds in estuarine water on embryo development through the assessment of seed viability after winter storage in three treatments: deionized (DI) water (control), autoclaved estuarine water (compounds), or filtered estuarine water (microbes + compounds). Afterwards seed viability was assessed using the tetrazolium chloride test. Results showed significantly greater viability in the DI treatment, indicating no influence from estuarine water. The second still ongoing experiment examines how microbes and chemical compounds affect the germination rates of seeds inoculated with marsh soil filtrate. Three treatments include: DI (control), DI base plus filtered soil inoculant (microbes + compounds), and DI plus autoclaved soil inoculant (compounds).
Speakers
SW

Sara Ward

sw25298@georgiasouthern.edu, College of Science and Mathematics
HJ

Heather Joesting

hjoesting@georgiasouthern.edu, College of Science and Mathematics
JE
NC
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Role of Sonography and MRI in Diagnosing Polycystic Ovary Syndrome (PCOS)
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects individuals with ovaries, characterized by an imbalance in reproductive hormones due to elevated androgen levels. This hormonal disturbance often results in irregular menstrual cycles, amenorrhea, and unpredictable ovulation. Ovarian morphology associated with PCOS typically includes multiple small follicular cysts and potential ovarian enlargement due to chronic anovulation. Clinical manifestations extend beyond reproductive irregularities and may include hirsutism, acne, weight gain, and infertility. The diagnostic approach for PCOS is multifaceted, combining clinical evaluation, laboratory testing, and imaging studies. Commonly, physicians employ a combination of physical examination, specific lab tests, and pelvic ultrasound to confirm the diagnosis. Pelvic ultrasound remains a fundamental method in diagnosing PCOS, with several sonographic parameters being used to distinguish polycystic ovaries from healthy ovaries. Key sonographic indicators include increased ovarian volume, increased follicle count, distinctive peripheral follicle distribution, and heightened ovarian stromal echogenicity. These parameters, particularly ovarian volume and follicle count, serve as reliable markers for PCOS, with peripheral follicle distribution being an especially distinctive indicator of the condition. Enhanced ovarian stromal echogenicity suggests potential reproductive dysfunction. In addition to these methods, magnetic resonance imaging (MRI) is another imaging modality that may be used to assess ovarian morphology. MRI provides insights similar to pelvic ultrasound, allowing for the measurement of ovarian volume and follicle count, as well as observation of follicular distribution patterns. The integration of MRI in the diagnostic process enhances the accuracy of PCOS evaluation. Thus, a combination of clinical, laboratory, and advanced imaging techniques is essential for the precise diagnosis of PCOS.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
JP

Jordan Play

jc47061@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Role of Sonography in Sports Medicine
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
The role of sonography in sports medicine is increasing as research is done on the benefits and range of uses. Sports physicians can use ultrasound to enhance diagnostic accuracy and treatment of pathologies. Research on this topic showed many instances where MSK ultrasound is being integrated into the sports medicine field. Physical therapists can use MSK ultrasound to treat knee, ankle, and other pathologies. There is also an increasing importance of integrating ultrasound into the curriculum for athletic training students to help with the diagnosis and treatment of injuries. When comparing other forms of imaging techniques for knee joint pathologies, it can be concluded that MRI is one of the most widely used tools. However, research stated that high-resolution sonography is better than MRI when comparing costs and availability. Collaboration between sports medicine and sonography programs would be beneficial in integrating the different modalities into both fields. 
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
TL

Taylor Langford

tl10957@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Roles of Ultrasound (US) and Computed tomography (CT) in the imaging and Diagnosis of Patients with Kidney Failure
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
This research poster is about the roles of ultrasound (US) and computed tomography (CT) in the imaging and diagnosis of patients with kidney failure. It emphasizes their strengths, weaknesses, and ability to diagnose accurately. Kidney failure is described as the partial or complete loss of kidney function. There are two main kinds of kidney failure, acute and chronic. Acute kidney failure happens suddenly, usually in people who were injured or are already critically ill. Chronic kidney disease develops over time and may not cause symptoms until much later. It is necessary to be precise and timely in imaging to aid in the clinical diagnosis and treatment of the patient. The faster kidney failure is caught and diagnosed, the better off the patient will be. The benefits of ultrasound include its accessibility, lack of ionizing radiation, and cost-effectiveness. It serves as a primary diagnostic tool and is useful in evaluating kidney size, structure, and any possible obstructions. Its strengths lie in the initial assessment and ongoing monitoring of the patient. On the other hand, CT imaging offers higher resolution and detailed anatomical information, crucial for detecting complex pathologies such as renal masses, and complications not as easily visualized by ultrasound. This paper reviews comparative studies, explaining situations where the benefits of using CT outweigh its higher cost and radiation exposure, and the benefits of using US for continued monitoring. The combined use of these imaging modalities can enhance diagnostic accuracy, improve patient outcomes, and optimize the management of kidney failure. This paper discusses the need for a tailored imaging approach, considering patient-specific factors and clinical scenarios, to utilize the strengths of both ultrasound and computed tomography in the evaluation of kidney failure.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
GD

Grace Deemer

ge01757@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The search continues: Targeting PRL3 through a high-throughput virtual screening campaign
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
The phosphatase of regenerating liver 3, or PRL3, is one of the most promising targets among the protein tyrosine phosphatase superfamily. It is known to regulate several pathways related to oncogenesis and increased metastasis. As such, several on-going drug discovery programs target PRL3 towards the development of migrastatics. We have identified several molecules with validated binding and modest inhibition against PRL3. While these molecules provide scaffold for development of more inhibitors, they currently have weak inhibitory activity and are still being developed. This project launched a high-throughput virtual screening campaign targeting a pocket that was previously identified through simulations and computational analysis. This virtual screening uses a library of >3 million lead-like molecules. Preliminary analysis revealed that several top binders have structural similarity to previous hits. Clustering analysis will identify other unique structural features based on this screen to support drug discovery against PRL3.
Speakers
GB

Grace Bennett

gs09195@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Use of CT and Ultrasound in Diagnosing Gallbladder Diseases
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)

Gallbladder disease is an extremely common set of disorders that appears in many patients. The two most common modalities used to examine the gallbladder are CT and ultrasound. Ultrasound is typically used first due to it being less expensive, fairly accurate, and using sound waves instead of radiation. However, ultrasound is dependent on the user or can miss diseases due to patient body habitus. This is where CT comes in, being able to visualize the gallbladder very well and being extremely accurate in finding gallbladder disease regardless of patient body habitus. However, it uses radiation and could be uncomfortable for the patient. A good goal for both modalities would be to better understand the other modality, its benefits, and its shortcomings so we can get a better idea of what to expect on both sides when looking for gallbladder disease so as to further reduce the likelihood of missing it.
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
NE

Nicole East

ne02420@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

The Use of Ultrasound in Determining Brain Abnormalities in Preterm Infants
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
My topic for the research assignment is “The Role of Ultrasound in Diagnosing Abnormalities in Preterm Infants”. Ultrasound is a great way to diagnose abnormalities in preterm infants because it is non-invasive, real-time, and no radiation is used. Some of the preterm abnormalities could include: hydrocephalus, intracranial hemorrhage, brain edema, choroid plexus cyst, and etc. Cranial ultrasounds are some of the most important for infants because their real-time imaging can see the anatomy and functional irregularity. The real-time imaging helps with a quick diagnosis for neurodevelopmental disabilities. These disabilities or irregularities need an early diagnosis so it can be treated or managed better. After reviewing the research articles I have chosen, I discovered that they mainly focus on abnormalities of the brain or lungs. Although, this is typically more commonly diagnosed in infants; there are other abnormalities that need to be diagnosed. 
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
KC

Kaley Carter

kc26815@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Therapeutic Ultrasound
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Therapeutic ultrasound is a type of ultrasonic procedure that is a noninvasive treatment in which sound waves are used to penetrate soft tissues which increases blood flow. This treatment is used to relieve pain, improve circulation, and encourage tissue healing. Therapeutic ultrasound is mainly used to treat various musculoskeletal pathologies, soft tissue shoulder pathology, and myofascial pain. My research is to see how beneficial therapeutic ultrasound is and what effects it has on the body. I want to see if therapeutic ultrasound does more good than harm since it is noninvasive and uses sound waves instead of radiation. Issues related to therapeutic ultrasound are superficial burns to the skin when used for long periods of time. When using high intensity focused ultrasound (HIFU), it is important for tissue changes to be monitored in order to confirm the treatment has been attained. There are two methods used for treatment monitoring and image guidance which is magnetic resonance imaging (MRI) and ultrasound. MRI imaging can measure temperature changes during therapy within the treatment zone of the therapeutic ultrasound procedures. Special clinical systems have ultrasound therapy subsystems integrated into MRI imagers for treatments of uterine fibroids, breast cancer, and prostate cancer management. It was interesting to find out how MRI and ultrasound helped each other in treatment options. The current research on therapeutic ultrasound is to determine the effectiveness of this treatment option and how safe this treatment method is compared to other modalities. 
Speakers
MB

Myka Bussey-Campbell

mcampbell@georgiasouthern.edu, Waters College of Health Professions
YD

Yvonne Dillion

ydillon@georgiasouthern.edu, Waters College of Health Professions
NB

Natalie Belair

nb10954@georgiasouthern.edu, Waters College of Health Professions
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Tracing the history of structural biology through three decades of PTP1B in the Protein Data Bank
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
The Protein Data Bank (PDB) is a database for experimentally determined structures of biomacromolecules. To date, there are >230,000 structures of proteins and nucleic acids in the PDB, which celebrated its 50th year in 2021. Throughout its existence, it drove the development of structural biology as a field. PTP1B, a founding member of the human protein tyrosine phosphatase superfamily, is an interesting case study. The first PTP to be purified, PTP1B is also the first one to be structurally characterized. The first crystal structure of PTP1B was deposited in the PDB in 1994 and now accounts for >400 entries. It has served not only as a model to study PTP structures but also as a model system for the study of protein structure and dynamics. Examination of PTP1B structures within the PDB tells a story that reflects the evolution of structural biology as it now enters its dynamic era.
Speakers
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
HC

Hailey Chen

hc09542@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Use of duckweed to reduce algae in aquaponics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Aquaponics is a constructed ecosystem combining aquaculture and nitrifying bacteria to provide nutrient rich water to grow plants directly in water (hydroponics). Algae can lead to mechanical issues by clogging tubing and pumps, as well as competing for nutrients with plants. The objective of the experiment was to use interspecies competition and the reduction of light to reduce algae biofouling. Duckweed (Lemna minor) was added to an existing aquaponics system in an area exposed to sunlight to induce interspecies competition with the algae. The experimental set up consisted of multiple replicates of 360 cm2 floating micro-ponds of landscaping fabric, foam pool noodles, and ~75% cover of Lemna minor. Treatment #1: fabric and Lemna minor. Treatment #2: fabric only, and Control: neither. The expected results include whether this method reduces algae growth, due to decreased light exposure and/or competition for resources with Lemna minor. The experiment will be conducted March-April 2025. 
Speakers
ER

Emma Riley

er11152@georgiasouthern.edu, College of Science and Mathematics
BB

Brigette Brinton

bbrinton@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

Variation in Fungal Endophytes in Yaupon Holly Tea Leaves
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
Fungi living inside plants, called fungal endophytes, can produce novel antibiotics and other interesting compounds for use by humans. This project explores the fungal endophytes of the Yaupon Holly plant, Ilex vomitoria, used as an alternative to tea.  We ask, “Are there differences in the fungal endophytes found between male and female Yaupon Holly plants?” and “Are there differences in the fungal endophytes in young leaves of Yaupon Holly compared to the older, established leaves?”  Leaves from 3 male and 3 female plants were sampled, including from young and older leaves. Six random leaflets were surface-sterilized and plated on growth media.  Fungi that grew from the leaflet pieces were subcultured, and morphologies, such as color, growth pattern, and colony texture, were cataloged.  Female leaves had twice as many unique fungi compared to male plants. There was little difference in the fungi found in young versus older leaves. 
Speakers
SG

Sara Gremillion

sgremillion@georgiasouthern.edu, College of Science and Mathematics
TB

Taryn Black

tb27415@georgiasouthern.edu, Waters College of Health Professions
JT

Jessica Tucker

jt27634@georgiasouthern.edu, College of Science and Mathematics
DR

Dominique Rembert

dr16692@georgiasouthern.edu
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:15pm EDT

When Medicine Meets Genetics: How a Single Mutation can Alter Treatment
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)

Lifestyle, hormones, age, environment, and genetics are all contributing factors to how individuals respond to medications. Genetics play a large role and even a single mutation in a protein can alter how they respond to treatments. A well studied example of this is a mutation found in the beta-2 adrenergic receptor, also known as ADRB2. Functional polymorphisms of ADRB2 have been shown to lead to diseases such as asthma and chronic obstructive pulmonary diseases (COPD). Both asthma and COPD are widely studied and several medications are on the market that effectively treat these diseases. A single mutation in ADRB2 can alter how patients with asthma, COPD, or other breathing problems, respond to these otherwise effective treatments. Specifically, the Thr164Ile mutation changes the affinity of said drugs to the ADRB2 receptor, making them less effective. Determining one's genetic makeup can determine what medications will be most effective for them.
Speakers
GB

Grace Bennett

gs09195@georgiasouthern.edu, College of Science and Mathematics
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
ME
TM
DR
Tuesday April 22, 2025 1:15pm - 3:15pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon

1:30pm EDT

Targeting the orphan PTP in Streptococcus pyogenes through combined in silico and in vitro screening
Tuesday April 22, 2025 1:30pm - 3:30pm EDT
Savannah Ballroom (211A)
S. pyogenes is a gram-positive human pathogen that has been linked to various diseases from skin infections to necrotizing fasciitis and rheumatic heart disease. The orphan protein tyrosine phosphatase from S. pyogenes (SP-PTP) was recently identified as a major virulence regulator, with studies showing that the knockdown of SP-PTP leads to reduced growth, impaired cell division, and decreased ability to invade host cells, exhibiting its importance in S. pyogenes pathogenesis. This makes it a viable target for new antibiotics, specifically targeting bacterial virulence. This project aims to identify small-molecule inhibitors of SP-PTP. An available crystal structure of SP-PTP shows high similarity with other low molecular weight PTPs (LMWPTPs). Using this structure, computational analysis of potential druggable pockets was performed. Consensus pockets were identified using FTMap and DoGSite and further validated by molecular dynamics druggability simulations. A virtual screening of a panel of FDA-approved drugs was also performed targeting these pockets.
Speakers
MD

Mark dela Cerna

mdelacerna@georgiasouthern.edu, College of Science and Mathematics
PR

Pitts, Ruby

rm23560@georgiasouthern.edu, College of Science and Mathematics
Tuesday April 22, 2025 1:30pm - 3:30pm EDT
Savannah Ballroom (211A)
  Poster Presentation - Afternoon
 
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